One Vaccine Shrank Tumors Across 4 Cancer Types in Mice
A new cancer vaccine targeting aging cells around tumors trained the immune system to clear senescent tissue in preclinical mouse studies spanning four distinct cancer types.
Why Promising Cancer Research Takes Decades to Reach Patients
Why is cancer research taking so long to find a cure? This post breaks down a Journal of Translational Medicine editorial on the structural forces slowing progress from lab findings to patient care.
Up to 90% of Tumor Immune Targets Hidden from Standard Tests
Why doesn't immunotherapy work for my cancer? This post covers new research on hidden tumor targets in non-coding DNA that standard mutation tests completely miss.
New Framework Would Use Patient Data Earlier to Guide Drug Research
What is a Phase 0 clinical trial and who qualifies? This post covers a proposed framework that would bring human biological data into drug research earlier than the current model allows.
Known Mutations May Not Be Driving Immunotherapy Failure
New research into cancer "dark matter" reveals hidden cancer signals immune system can't find, offering a fuller picture of why immunotherapy fails for many patients.
72.93% Tumor Inhibition Seen in Dual-Drug Nanoparticle Mouse Study
Can nanotechnology reduce breast cancer drug side effects? This preclinical study found a dual-drug nanoparticle system cut tumor growth by 72.93% in mice.
Stressed Cancer Cell Batteries Leak Signals That Mimic a Virus
This review paper examines how cold tumor biology and mitochondrial stress connect, exploring what the cGAS-STING pathway reveals about cold tumor how to make immunotherapy work.