Zombie cells block stem cell repair, mouse study reveals
This mouse study explores how senolytic immunotherapy pluripotent MSC combination therapy performs when aging tissue is cleared of senescent cells before stem cell transplantation.
Heart Failure Patients Report Better Daily Life in Early Stem Cell Study
This Phase 1/2 trial post covers early clinical findings on stem cell IV infusion for heart failure, exploring whether a simple infusion could replace invasive delivery methods.
Cord Tissue Stem Cells Delivered by IV Reduced Inflammation and Improved Strength in Trial
Can stem cells improve strength and energy in older adults? This post covers what a randomized controlled trial found when umbilical cord stem cells were infused into frail older adults.
Wharton’s Jelly ‘Stem Cell’ Products May Contain Virtually No Living Stem Cells
Umbilical cord stem cell therapy what am I really getting is explored here, as lab testing of six Wharton's jelly products found the cellular content far below therapeutic levels.
79% of Treated Skin Tumors Responded to Cream Plus Radiation
A phase I/II trial on combining radiation with immunotherapy for breast cancer recurrence found 79% of treated skin tumors responded when imiquimod cream was paired with targeted radiation.
How Blocking a Stress Signal Helps Immune Cells Fight Tumors Again
This post covers a mouse model study exploring triple negative breast cancer immunotherapy options through a three-drug approach targeting T cell exhaustion in the tumor microenvironment.
One Vaccine Shrank Tumors Across 4 Cancer Types in Mice
A new cancer vaccine targeting aging cells around tumors trained the immune system to clear senescent tissue in preclinical mouse studies spanning four distinct cancer types.
Why Promising Cancer Research Takes Decades to Reach Patients
Why is cancer research taking so long to find a cure? This post breaks down a Journal of Translational Medicine editorial on the structural forces slowing progress from lab findings to patient care.
Up to 90% of Tumor Immune Targets Hidden from Standard Tests
Why doesn't immunotherapy work for my cancer? This post covers new research on hidden tumor targets in non-coding DNA that standard mutation tests completely miss.
New Framework Would Use Patient Data Earlier to Guide Drug Research
What is a Phase 0 clinical trial and who qualifies? This post covers a proposed framework that would bring human biological data into drug research earlier than the current model allows.
Known Mutations May Not Be Driving Immunotherapy Failure
New research into cancer "dark matter" reveals hidden cancer signals immune system can't find, offering a fuller picture of why immunotherapy fails for many patients.
390 Million Annual Infections Drive Search for New Dengue Targets
How dengue virus evades the immune system? This 2025 Virology Journal review maps the metabolic processes dengue hijacks inside host cells to replicate before immunity can respond.